Tuesday, 27 July 2021

AKI

 CASE OF A 60YR OLD FEMALE WITH PEDAL EDEMA

 


ACUTE KIDNEY INJURY SECONDARY TO UROSEPSIS

June 19, 2021

A 60yr old female presented to the OPD with chief complaints of pedal edema since 10 days, decreased urine output since 10 days and fever since 10 days.


History of present illness:


The patient was apparently asymptomatic 10years back following which she was diagnosed with DM2 on checkup and on Teneligliptin 20 mg. In 2019 ( 2 years ago) she developed fever, shortness of breath and pedal edema and diagnosed with Acute kidney injury secondary to urosepsis and resolved conservatively after dialysis (4 sessions)


Now presented with history of fever, high grade since 10 days, not associated with vomiting and loose stools . Patient complaints pedal edema bilateral and pitting type, with decreased urine output and burning micturition.


History of past illness:


Outside reports suggest acute kidney injury. Known case of diabetes mellitus since 10 years and on tab Teneligliptin 20 mg and not known case of hypertension, bronchial asthma, tuberculosis.


Personal history:


Married 

Mixed diet

Normal Apetite 

Adequate sleep

Bowel movement is regular

Decreased urine output and burning micturition

With no known allergies.

Consumes alcohol occasionally.


Family history:


No significant family history


General examination:


There is Pallor 

There is no Icterus, cyanosis, clubbing

Generalized Lymphadenopathy

Edema is seen bilaterally witch is Pitting type pedal edema. 

Vitals:

Temperature afebrile

Pulse rate is 111 beats per minute

Respiratory rate is 24 cycles per minute

Blood pressure measured on the left hand is 170/110 mm of Hg

Oxygen saturation at room air is 90 arm per mm Hg





Systemic examination:


Abdominal system:

No scars, sinuses, or any engorged veins.

Hernial orifices intact

Tenderness or guarding absent

No enlargement of liver, kidneys, or spleen

No ascites

Bowel sounds were normal.

Cardiovascular system:

cardiac sounds S1 S2 heard.

No cardiac murmurs

Thrills absent

Respiratory system:

No chest wall deformity 

Trachea central

Expansion is symmetrical

Percussion note is resonant

Breath sounds normal, no wheeze or crackles heard.

Vocal resonance normal and symmetrical


Central nervous system:

No focal abnormality detected

Higher mental functions intact 

Cranial nerves intact 

reflxes normal

Speech normal


Provisional diagnosis:

Acute kidney injury secondary to urosepsis


Investigations ordered:

14/06/21

1. Complete urine examination: 




2. ECG:


15/06/21:

1. Serum creatinine:


2. Blood sugar Fasting:


3. Blood sugar Random:



4. Blood Urea:


5. Serum Electrolytes:



6. Serum Potassium:


7. Urinary Chloride:


8 URINARY POTASSIUM



9. Urinary Sodium:



16/06/21

1. Serum Electrolytes:



2. Serum Creatinine:



3. Haemogram:



4. Blood urea:



5. ABG:



18/6/21

1. Serum creatinine:



2. Serum Electrolytes:



3.Haemogram:



4.Blood urea:



21/6/21

1. Complete Blood Picture (CBP)



Blood urea:


15/6/21 - 65 mg/dl

16/6/21 - 62 mg/dl

18/6/21 - 76 mg/dl

21/6/21 - 81mg/dl


Serum creatinine:


15/6/21 - 3.4 mg/dl

16/6/21 - 3.4 mg/dl

18/6/21 - 3.2 mg/dl

21/6/21 - 3.1 mg/dl


Total leukocytes count:


16/6/21 - 24700

18/6/21 - 26500

21/6/21 - 31700


Serum Electrolytes:


15/6/21 - Na: 139 ; K: 5.2 ; Cl: 106

16/6/21 - Na: 138 ; K: 5.1 ; Cl: 105

18/6/21 - Na: 136 ; K: 4.9 ; Cl: 102

21/6/21 - Na: 134 ; K: 5.5 ; Cl: 98


Diagnosis:


Acute kidney injury secondary to urosepsis with hyperkalemia ( resolved)

With anenmia of chronic disease 


Treatment:


15/06/21:


Treatment:

Inj LASIX 40mg (8am- 2pm -8pm)

IVF - NS @ UO + 50 ml/hr



15/6/21, 5:30 p.m.


Treatment:

Inj LASIX 40mg (8am -2pm -8pm)

IVF - NS @ UO + 50 ml/hr



16/6/21


Treatment:

 Inj LASIX 40 mg IV/TID 1 -1 - 1

 IVF - NS @ UO + 50 ml/hr

 Inj MAGNEXFORTE 1.5 gm/IV/BD

 Tab NODOSIS - XT PO/OD

 Inj HAI s/c

 Neb plain Asthalin 4 respules 1 - 1 - 1 - 1



17/6/21


Treatment:

 Inj LASIX 40 mg IV/TID 1 -1 - 1

 IVF - NS @ UO + 50 ml/hr

 Inj MAGNEXFORTE 1.5 gm/IV/BD

 Tab NODOSIS - XT PO/OD

 Tab OROFEA - XT PO/OD

 Inj HAI s/c

 Neb plain Asthalin 2 respules

 Strict I/O charting



18/6/21


Treatment:

 Inj LASIX 40 mg IV/TID 1 -1 - 1

 IVF - NS @ UO + 50 ml/hr

 Inj MAGNEXFORTE 1.5 gm/IV/BD

 Tab NODOSIS - XT PO/OD

 Tab OROFEA - XT PO/OD

 Inj HAI s/c

 Neb plain Asthalin 2 respules QID

 Strict I/O charting

Tab ULTRACET 1/2 tab QID 1/2 - 1/2 - 1/2 - 1/2


19/6/21


Treatment:

 Inj LASIX 40 mg IV/TID 1 -1 - 1

 IVF - NS @ UO + 50 ml/hr

 Inj MAGNEXFORTE 1.5 gm/IV/BD

 Tab NODOSIS - 500 mg PO/OD

 Tab OROFEA - XT PO/OD

 Inj HAI s/c

 Neb plain Asthalin 2 respules QID

 Strict I/O charting

 Tab ULTRACET 1/2 tab QID 1/2 - 1/2 - 1/2 - 1/2

Expected discharge summary:-

A 60yr old female presented to the OPD with chief complaints of pedal edema since 10 days, decreased urine output since 10 days and fever since 10 days.


History of present illness:


The patient was apparently asymptomatic 10 years back following which she was diagnosed with DM2 on checkup and on Teneligliptin 20 mg. In 2019 ( 2 years ago) she developed fever, shortness of breath and pedal edema and diagnosed with Acute kidney injury secondary to urosepsis and resolved conservatively after dialysis (4 sessions)


Now presented with history of fever, high grade since 10 days, not associated with vomiting and loose stools . Patient complaints pedal edema bilateral and pitting type, with decreased urine output and burning micturition.


History of past illness:


Outside reports suggest acute kidney injury. Known case of diabetes mellitus since 10 years and on tab Teneligliptin 20 mg and not known case of hypertension, bronchial asthma, tuberculosis.


Personal history:


Married 

Mixed diet

Noamal Appetite 

Adequate sleep

Bowel movement is regular

Decreased urine output and burning micturition

With no known allergies.

Consumes alcohol occasionally.


Family history:


No significant family history


General examination:


There is Pallor 

There is no Icterus, cyanosis, clubbing

Generalized Lymphadenopathy

Edema is seen bilaterally witch is Pitting type pedal edema. 

Vitals:

Temperature afebrile

Pulse rate is 111 beats per minute

Respiratory rate is 16 breaths per minute

Blood pressure measured on the left hand is 170/110 mm of Hg

Oxygen saturation at room air is 90 arm per mm Hg

Systemic examination:


Abdominal system:

No scars, sinuses, or any engorged veins.

Hernial orifices intact

Tenderness or guarding absent

No enlargement of liver, kidneys, or spleen

No ascites

Bowel sounds were normal.

Cardiovascular system:

cardiac sounds s1 and s2 heard normally

Apex beat located in 5th ICS, medial to the mid-clavicular line.

No cardiac murmurs

Thrills absent

Respiratory system:

No chest wall deformity 

Trachea central

Expansion is symmetrical

Percussion note is resonant

Breath sounds normal, no wheeze or crackles heard.

Vocal resonance normal and symmetrical



Central nervous system:

No focal abnormality detected

Higher mental functions intact 

Cranial nerves intact 

Speech normal


Provisional diagnosis:

Acute kidney injury secondary to urosepsis


Course in the hospital:-

Day 1:-

Treatment:

Inj LASIX 40mg (8am- 2pm -8pm)

IVF - NS @ UO + 50 ml/hr



Day 2:-


 Inj LASIX 40 mg IV/TID 1 -1 - 1

 IVF - NS @ UO + 50 ml/hr

 Inj MAGNEXFORTE 1.5 gm/IV/BD

 Tab NODOSIS - XT PO/OD

 Inj HAI s/c

 Neb plain Asthalin 4 respules [ 1 - 1 - 1 - 1 ]



Day 2:-

same treatment was continued

 Tab OROFEA - XT PO/OD

 Strict I/O charting was advised



Day 3:-same treatment was continued

Tab ULTRACET 1/2 tab QID [ 1/2 - 1/2 - 1/2 - 1/2 ] was added.


Day 4 and day 5:-same treatment was continued



Day 6:-

Same treatment was continued

 Tab Norflox 200 mg PO/OD was added


Day 7:-

Same treatment was continued

 Tab SHELCAL-CT PO/OD was added


Day 8:-same treatment was continued








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